HDAC1 fine-tunes Th17 polarization in vivo to restrain tissue damage in fungal infections

Summary: Histone deacetylases (HDACs) contribute to shaping many aspects of T cell lineage functions in anti-infective surveillance; however, their role in fungus-specific immune responses remains poorly understood. Using a T cell-specific deletion of HDAC1, we uncover its critical role in limiting...

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Principais autores:	Philipp Penninger, Helena Brezovec, Irina Tsymala, Magdalena Teufl, Trinh Phan-Canh, Tamires Bitencourt, Marie Brinkmann, Walter Glaser, Wilfried Ellmeier, Michael Bonelli, Karl Kuchler
格式:	Artigo
語言:	Inglês
出版:	Elsevier 2024-12-01
叢編:	Cell Reports
主題:	CP: Immunology
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2211124724013445
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