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Identification of the SIRT1 gene's most harmful non-synonymous SNPs and their effects on functional and structural features-an in silico analysis [version 2; peer review: 2 approved]

Introduction The sirtuin (Silent mating type information regulation 2 homolog)1(SIRT1) protein plays a vital role in many disorders such as diabetes, cancer, obesity, inflammation, and neurodegenerative and cardiovascular diseases. The objective of this in silico analysis of SIRT1's functional singl...

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Autori principali: Desy Thayyil Menambath, Usha Adiga, Vijith Shetty, Sachidananda Adiga, Tirthal Rai
Natura: Artigo
Lingua:Inglês
Pubblicazione: F1000 Research Ltd 2024-01-01
Serie:F1000Research
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Accesso online:https://f1000research.com/articles/12-66/v2
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