SPI1-Mediated Upregulation of the CST1 Gene as an Independent Poor Prognostic Factor Accelerates Metastasis in Esophageal Squamous Cell Carcinoma (ESCC) by Interacting with MMP2

Background: Esophageal squamous cell carcinoma (ESCC) is a highly lethal tumor type, but studies on the ESCC tumor microenvironment are limited. We found that cystatin SN (CST1) plays an important role in the ESCC tumor microenvironment. CST1 has been reported to act as an oncogene in multiple human...

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Autors principals:	Fei-Fei Luo, Jing Wang, Zhan-Fei Zhang, Si-Ting Lin, Tie-Jun Huang, Bao-Qi Liu, Mei-Ling Fan, Li-Xia Peng, Shu-Tao Zheng, Chang-Fu Yang, Bi-Jun Huang
Format:	Artigo
Idioma:	Inglês
Publicat:	IMR Press 2023-09-01
Col·lecció:	Frontiers in Bioscience-Landmark
Matèries:	cst1 esophageal squamous cell carcinoma (escc) metastasis prognostic biomarker tumor microenvironment (tme) matrix metalloproteinase (mmp)
Accés en línia:	https://www.imrpress.com/journal/FBL/28/9/10.31083/j.fbl2809212
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