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Cancer cell targeting by CAR-T cells: A matter of stemness

Chimeric antigen receptor (CAR)-T cell therapy represents one of the most innovative immunotherapy approaches. The encouraging results achieved by CAR-T cell therapy in hematological disorders paved the way for the employment of CAR engineered T cells in different types of solid tumors. This adoptiv...

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Sparad:
Huvudupphov: Caterina D’Accardo, Gaetana Porcelli, Laura Rosa Mangiapane, Chiara Modica, Vincenzo Davide Pantina, Narges Roozafzay, Simone Di Franco, Miriam Gaggianesi, Veronica Veschi, Melania Lo Iacono, Matilde Todaro, Alice Turdo, Giorgio Stassi
Materialtyp: Artigo
Språk:Inglês
Utgiven: Frontiers Media S.A. 2022-12-01
Serie:Frontiers in Molecular Medicine
Ämnen:
CAR-T cell therapy
immunotherapy
cancer stem cells
anti-cancer therapy
tumor microenvironment
Länkar:https://www.frontiersin.org/articles/10.3389/fmmed.2022.1055028/full
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