Acid-Catalyzed, Metal- and Oxidant-Free C=C Bond Cleavage of Enaminones: One-Pot Synthesis of 3,4-Dihydroquinazolines

In this study, we present the HOAc-catalyzed selective cleavage of the C=C double bond of enaminones, enabling the formation of a new C–N bond and a new C=N bond for the one-pot synthesis of 2-substituted 3,4-dihydroquinazolines directly from ynones and 2-(aminomethyl)anilines. This method operates...

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Päätekijät:	Ting Chen, Ting Huang, Moudan Ye, Jinhai Shen
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	MDPI AG 2025-01-01
Sarja:	Molecules
Aiheet:	3,4-dihydroquinazoline enaminones C–C bond cleavage ynones organic synthesis
Linkit:	https://www.mdpi.com/1420-3049/30/2/350
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