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MicroRNA-203 represses selection and expansion of oncogenic Hras transformed tumor initiating cells

In many mouse models of skin cancer, only a few tumors typically form even though many cells competent for tumorigenesis receive the same oncogenic stimuli. These observations suggest an active selection process for tumor-initiating cells. Here, we use quantitative mRNA- and miR-Seq to determine the...

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Bibliografische Detailangaben
Hauptverfasser: Kent Riemondy, Xiao-jing Wang, Enrique C Torchia, Dennis R Roop, Rui Yi
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications Ltd 2015-07-01
Schriftenreihe:eLife
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Online-Zugang:https://elifesciences.org/articles/07004
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