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Developmental regulation of the Tetrahymena thermophila origin recognition complex.

The Tetrahymena thermophila DNA replication machinery faces unique demands due to the compartmentalization of two functionally distinct nuclei within a single cytoplasm, and complex developmental program. Here we present evidence for programmed changes in ORC and MCM abundance that are not consisten...

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Autori principali: Po-Hsuen Lee, Xiangzhou Meng, Geoffrey M Kapler
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2015-01-01
Serie:PLoS Genetics
Accesso online:http://europepmc.org/articles/PMC4287346?pdf=render
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