Novel read density distribution score shows possible aligner artefacts, when mapping a single chromosome

Abstract Background The use of artificial data to evaluate the performance of aligners and peak callers not only improves its accuracy and reliability, but also makes it possible to reduce the computational time. One of the natural ways to achieve such time reduction is by mapping a single chromosom...

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Bibliografski detalji

Glavni autori:	Fedor M. Naumenko, Irina I. Abnizova, Nathan Beka, Mikhail A. Genaev, Yuriy L. Orlov
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2018-02-01
Serija:	BMC Genomics
Teme:	Next-generation sequencing DNA alignment Read density distribution
Online pristup:	http://link.springer.com/article/10.1186/s12864-018-4475-6
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