New Antifungal Compound: Impact of Cosolvency, Micellization and Complexation on Solubility and Permeability Processes
Poor solubility of new antifungal of 1,2,4-triazole class (S-119)—a structural analogue of fluconazole in aqueous media was estimated. The solubility improvement using different excipients: biopolymers (PEGs, PVP), surfactants (Brij S20, pluronic F-127) and cyclodextrins (α-CD, β-CD, 2-HP-β-CD, 6-O-...
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| Huvudupphov: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
MDPI AG
2021-11-01
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| Serie: | Pharmaceutics |
| Ämnen: | |
| Länkar: | https://www.mdpi.com/1999-4923/13/11/1865 |
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