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Silencing LCN2 suppresses oral squamous cell carcinoma progression by reducing EGFR signal activation and recycling

Abstract Background EGFR is an important signal involved in tumor growth that can induce tumor metastasis and drug resistance. Exploring targets for effective EGFR regulation is an important topic in current research and drug development. Inhibiting EGFR can effectively inhibit the progression and l...

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Principais autores: Zixian Huang, Xi Rui, Chen Yi, Yongju Chen, Rui Chen, Yancan Liang, Yan Wang, Weicheng Yao, Xiaoding Xu, Zhiquan Huang
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2023-03-01
coleção:Journal of Experimental & Clinical Cancer Research
Assuntos:
Oral squamous cell carcinoma
Lipocalin-2
EGFR
Metastasis
Proliferation
Nanoparticles
Acesso em linha:https://doi.org/10.1186/s13046-023-02618-z
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