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Enhanced skin delivery of vismodegib-loaded rigid liposomes combined with ethosomes

Vismodegib, first approved in 2012 for the treatment of basal cell carcinoma, is an inhibitor of the Hedgehog signaling pathway that becomes active in certain tumors. However, its secondary effects after oral administration and systemic distribution are severe. In this study, we loaded vismodegib in...

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主要な著者: E.T. Aguayo Frías, D. Maza Vega, M.N. Calienni, C. Lillo, D.S. Vazquez, S.d.V. Alonso, J. Montanari
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2023-11-01
シリーズ:OpenNano
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オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S2352952023000658
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