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Deficiency of the LIM-only protein FHL2 reduces intestinal tumorigenesis in Apc mutant mice.

BACKGROUND: The four and a half LIM-only protein 2 (FHL2) is capable of shuttling between focal adhesion and nucleus where it signals through direct interaction with a number of proteins including beta-catenin. Although FHL2 activation has been found in various human cancers, evidence of its functio...

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Principais autores: Charlotte Labalette, Yann Nouët, Florence Levillayer, Sabine Colnot, Ju Chen, Valere Claude, Michel Huerre, Christine Perret, Marie-Annick Buendia, Yu Wei
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science (PLoS) 2010-01-01
סדרה:PLoS ONE
גישה מקוונת:http://europepmc.org/articles/PMC2860980?pdf=render
תגים: הוספת תג
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