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Metformin provides superior neuroprotective potential compared to semaglutide in preventing diabetes-associated Alzheimer’s disease via dual actions

Abstract Background Alzheimer’s disease (AD) and Diabetes Mellitus Type II (DM2) share overlapping biological mechanisms, and diabetes increases the risk of developing AD. Treatments that modify the course of diabetes, such as metformin and semaglutide, have been proposed to protect the brain, but t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Andrea Georgiou, Panos Zanos, Anna Onisiforou
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Portfolio 2026-02-01
Cyfres:Communications Medicine
Mynediad Ar-lein:https://doi.org/10.1038/s43856-026-01471-3
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