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PPARα exacerbates Salmonella Typhimurium infection by modulating the immunometabolism and macrophage polarization

Salmonella enterica serovar Typhimurium (STm) is a causative pathogen for robust inflammatory gastrointestinal disease and can lead to systemic infection. Eicosanoids, bioactive lipid mediators, play a crucial role in modulating both the induction and resolution of inflammatory responses during an i...

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Principais autores: Jessica R. Taddeo, Naomi Wilson, Anita Kowal, Joris Beld, Andres Klein-Szanto, Çagla Tükel, Vincent C. Tam
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2024-12-01
Serier:Gut Microbes
Fag:
Salmonella Typhimurium
lipidomic analysis
eicosanoids
fatty acids
macrophages
Online adgang:https://www.tandfonline.com/doi/10.1080/19490976.2024.2419567
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