Mechanisms underlying genome instability mediated by formation of foldback inversions in Saccharomyces cerevisiae

Foldback inversions, also called inverted duplications, have been observed in human genetic diseases and cancers. Here, we used a Saccharomyces cerevisiae genetic system that generates gross chromosomal rearrangements (GCRs) mediated by foldback inversions combined with whole-genome sequencing to st...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Bin-zhong Li, Christopher D Putnam, Richard David Kolodner
Formato:	Artigo
Idioma:	Inglês
Publicado em:	eLife Sciences Publications Ltd 2020-08-01
coleção:	eLife
Assuntos:	dna repair genome rearrangement translocation whole genome sequencing
Acesso em linha:	https://elifesciences.org/articles/58223
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!