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Emerging Role of High-Mobility Group Box 1 (HMGB1) in Liver Diseases

Abstract Damage-associated molecular pattern (DAMP) molecules are essential for the initiation of innate inflammatory responses to infection and injury. The prototypic DAMP molecule, high-mobility group box 1 (HMGB1), is an abundant architectural chromosomal protein that has location-specific biolog...

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Main Authors: Ruochan Chen, Wen Hou, Qiuhong Zhang, Rui Kang, Xue-Gong Fan, Daolin Tang
Format: Artigo
Language:Inglês
Published: BMC 2013-11-01
Series:Molecular Medicine
Subjects:
High Mobility Group Box (HMGB1)
DAMP Molecules
HMGB1 Activity
HMGB1 Signaling
HMGB1 Release
Online Access:https://doi.org/10.2119/molmed.2013.00099
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