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Output-Specific Adaptation of Habenula-Midbrain Excitatory Synapses During Cocaine Withdrawal

Projections from the lateral habenula (LHb) control ventral tegmental area (VTA) neuronal populations’ activity and both nuclei shape the pathological behaviors emerging during cocaine withdrawal. However, it is unknown whether cocaine withdrawal modulates LHb neurotransmission onto subsets of VTA n...

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Principais autores: Joseph Clerke, Patricia Preston-Ferrer, Ioannis S. Zouridis, Audrey Tissot, Laura Batti, Fabian F. Voigt, Stephane Pagès, Andrea Burgalossi, Manuel Mameli
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-03-01
Serier:Frontiers in Synaptic Neuroscience
Fag:
ventral tegmental area
lateral habenula
cocaine
synaptic plasticity
glutamatergic transmission
Online adgang:https://www.frontiersin.org/articles/10.3389/fnsyn.2021.643138/full
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