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Case Report: Synaptophysin-positive SMARCA4-deficient undifferentiated thoracic tumour: a diagnostic pitfall with therapeutic implications

SMARCA4-deficient undifferentiated thoracic tumour (SMARCA4-UT) is a rare and highly aggressive malignancy with a poor prognosis and no established standard therapy. Isolated synaptophysin (Syn) expression may further complicate its differential diagnosis, particularly from neuroendocrine tumours. W...

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Principais autores: Chang-Sen Bai, Xiong-Wen He, Shu Lin, Bai-Cheng Xu, Qi-Xing Yan, Ming-Fa Wang, Yue-Can Zeng, Jing-Ru Luo, Wen-Jun Tang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-06-01
coleção:Frontiers in Oncology
Assuntos:
case report
diagnostic pitfall
gene regulation
SMARCA4-UT
Syn
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fonc.2026.1871202/full
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