Multiomics assessment of lung adenocarcinoma subtypes defined through tumor purity-adjusted DNA methylation

Abstract Background Molecular subtypes of lung adenocarcinoma (LUAD) with varying prognosis and characteristics have been proposed based on one or two-dimensional studies but are not yet implemented into clinical routine. Epigenetic modifications in cancer cells are independent of sequence variants,...

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Библиографические подробности

Главные авторы:	Deborah F. Nacer, Elsa Arbajian, Srinivas Veerla, Mattias Aine, Mats Jönsson, Frida Rosengren, Anna Karlsson, Annette Salomonsson, Sofi Isaksson, Maria Planck, Johan Staaf
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2026-02-01
Серии:	Genome Medicine
Предметы:	Epigenetics Primary lung cancer Subclassification Tumor intrinsic patterns
Online-ссылка:	https://doi.org/10.1186/s13073-026-01609-x
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