A Novel Mutation in the NBD Domain of NLRC4 Causes Mild Autoinflammation With Recurrent Urticaria

BackgroundNOD-like receptor family CARD-containing 4 protein (NLRC4) is a cytosolic protein that forms an inflammasome in response to flagellin and type 3 secretion system (T3SS) proteins from invading Gram-negative bacteria. NLRC4 mutations have been recently identified in early-onset severe autoin...

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Autors principals:	Li Wang, Wen Wen, Mengyue Deng, Yue Li, Gan Sun, Xiaodong Zhao, Xuemei Tang, Huawei Mao
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2021-06-01
Col·lecció:	Frontiers in Immunology
Matèries:	NLRC4 novel mutation autoinflammatory disease mild phenotype urticaria
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.674808/full
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