Heterologous Expression of Type II PKS Gene Cluster Leads to Diversified Angucyclines in <i>Streptomyces albus</i> J1074

Heterologous expression has emerged as an effective strategy in activating <i>Streptomyces</i> cryptic gene clusters or improving yield. Eight compounds were successfully obtained by heterologous expression of the type II PKS gene cluster <i>spi</i> derived from marine <i>Streptomyces</i> sp. HDN155...

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Autori principali:	Xiaoting Zhang, Falei Zhang, Chen Li, Jiayi Li, Xiao Xu, Tianjiao Zhu, Qian Che, Deihai Li, Guojian Zhang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2024-10-01
Serie:	Marine Drugs
Soggetti:	heterologous expression II PKS marine <i>Streptomyces</i> angucycline
Accesso online:	https://www.mdpi.com/1660-3397/22/11/480
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