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Juglone induces ferroptosis in glioblastoma cells by inhibiting the Nrf2-GPX4 axis through the phosphorylation of p38MAPK

Abstract Background Ferroptosis, a non-apoptotic form of cell death induced by accumulation of free iron ions and lipid peroxidation, its importance for cancer treatment is gradually being recognized. Research on the anti-cancer mechanism of juglone is accumulating. However, the specific mechanism b...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Fangzhou Guo, Guoyuan Ling, Jianting Qiu, Jicheng Li, Yu Gan, YingYing Yu, Jiamei Tang, Ligen Mo, Haozhe Piao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMC 2024-03-01
Cyfres:Chinese Medicine
Pynciau:
Mynediad Ar-lein:https://doi.org/10.1186/s13020-024-00920-2
Tagiau: Ychwanegu Tag
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