Synthesis, Antimalarial Activity and Molecular Dynamics Studies of Pipecolisporin: A Novel Cyclic Hexapeptide with Potent Therapeutic Potential

Malaria, caused by <i>Plasmodium</i> species and transmitted by <i>Anopheles</i> mosquitoes, continues to pose a significant global health threat. Pipecolisporin, a cyclic hexapeptide isolated from <i>Nigrospora oryzae</i>, has emerged as a promising antimalarial candidate due to its potent biologic...

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Библиографические подробности

Главные авторы:	Nety Kurniaty, Taufik Muhammad Fakih, Rani Maharani, Unang Supratman, Ace Tatang Hidayat, Nurhidanatasha Abu Bakar, Xiaoshuang Wei
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2025-01-01
Серии:	Molecules
Предметы:	pipecolisporin cyclic hexapeptide solid-phase peptide synthesis (SPPS) antimalarial candidates computational studies
Online-ссылка:	https://www.mdpi.com/1420-3049/30/2/304
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