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Toxoplasma infection in male mice alters dopamine-sensitive behaviors and host gene expression patterns associated with neuropsychiatric disease.

During chronic infection, the single celled parasite, Toxoplasma gondii, can migrate to the brain where it has been associated with altered dopamine function and the capacity to modulate host behavior, increasing risk of neurocognitive disorders. Here we explore alterations in dopamine-related behav...

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Detalles Bibliográficos
Principais autores: Graham L Cromar, Jonathan R Epp, Ana Popovic, Yusing Gu, Violet Ha, Brandon J Walters, James St Pierre, Xuejian Xiong, John G Howland, Sheena A Josselyn, Paul W Frankland, John Parkinson
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2022-07-01
Series:PLoS Neglected Tropical Diseases
Acceso en liña:https://doi.org/10.1371/journal.pntd.0010600
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