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Sestrin2-mediated disassembly of stress granules dampens aerobic glycolysis to overcome glucose starvation

Abstract Sestrins are a small gene family of pleiotropic factors whose actions promote cell adaptation to a range of stress conditions. In this report we disclose the selective role of Sestrin2 (SESN2) in dampening aerobic glycolysis to adapt to limiting glucose conditions. Removal of glucose from h...

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Bibliografiske detaljer
Principais autores: Mingyue Li, Rick Francis Thorne, Ruijie Wang, Leixi Cao, Fangyuan Cheng, Xuedan Sun, Mian Wu, Jianli Ma, Lianxin Liu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2023-04-01
Serier:Cell Death Discovery
Online adgang:https://doi.org/10.1038/s41420-023-01411-3
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