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New insights into the mechanism of microvascular rarefaction via endothelial-mesenchymal transition in steroid-induced osteonecrosis of femoral head

Abstract This study aimed to investigate the potential role of endothelial-to-mesenchymal transition (EndMT) in steroid-induced osteonecrosis of the femoral head (SONFH), evaluate its association with microvascular rarefaction and tissue damage, and preliminarily explore whether glucocorticoid-induc...

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Main Authors: Xiaoqiang Yang, Peng Yang, Jiaru Liao, Fan Yang, Mincong He, Ziqi Li, Qiushi Wei, Wei He
Format: Artigo
Language:Inglês
Published: Nature Portfolio 2025-12-01
Series:Scientific Reports
Subjects:
EndMT
Microvascular rarefaction
SONFH
Online Access:https://doi.org/10.1038/s41598-025-30454-y
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