Co-Treatment with Ritonavir or Sertraline Enhances Itraconazole Efficacy Against Azole-Resistant <i>Trichophyton indotineae</i> Isolates

The treatment of azole-resistant <i>Trichophyton indotineae</i> poses a significant challenge for clinicians worldwide. Resistance mechanisms include amino acid substitutions in the sterol 14-α demethylase gene <i>Erg11B</i>, as well as overexpression of <i>Erg11B</i>. Additionally, efflux mechanism...

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Principais autores:	Anna Günther, Anke Burmester, Mario Fabri, Jörg Tittelbach, Cornelia Wiegand
格式:	Artigo
语言:	Inglês
出版:	MDPI AG 2025-09-01
丛编:	Journal of Fungi
主题:	antifungal resistance itraconazole ritonavir sertraline <i>Trichophyton</i> <i>indotineae</i>
在线阅读:	https://www.mdpi.com/2309-608X/11/10/698
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