A new pma1 mutation identified in a chronologically long-lived fission yeast mutant

We isolated a chronologically long-lived mutant of Schizosaccharomyces pombe and found a new mutation in pma1+ that encoded for an essential P-type proton ATPase. An Asp-138 to Asn mutation resulted in reduced Pma1 activity, concomitant with an increase in the chronological lifespan of this fission...

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Hlavní autoři:	Chikako Naito, Hirokazu Ito, Tomoko Oshiro, Hokuto Ohtsuka, Hiroshi Murakami, Hirofumi Aiba
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2014-01-01
Edice:	FEBS Open Bio
Témata:	Chronological lifespan Fission yeast Pma1
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2211546314000886
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