क्यूआर कोड

Paired ctDNA analysis reveals diverse resistance mechanisms to mobocertinib in EGFR exon 20 insertion NSCLC

BackgroundEpidermal growth factor receptor (EGFR) exon 20 insertion mutations in non-small cell lung cancer (NSCLC) represent a distinct molecular subset with limited response to conventional tyrosine kinase inhibitors (TKIs). Mobocertinib, a targeted EGFR exon 20 inhibitor, shows clinical activity,...

पूर्ण विवरण

में बचाया:
मुख्य लेखकों: Jinyong Kim, Geun-Ho Park, Sehhoon Park, Hyun Ae Jung, Se-Hoon Lee, Jin Seok Ahn, Myung-Ju Ahn, Jong-Mu Sun
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Frontiers Media S.A. 2026-05-01
श्रृंखला:Frontiers in Oncology
विषय:
ctDNA
EGFR exon 20 insertion
liquid biopsy
mobocertinib
non-small cell lung cancer
resistance mechanisms
ऑनलाइन पहुंच:https://www.frontiersin.org/articles/10.3389/fonc.2026.1827867/full
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