Monoallelic expression and epigenetic inheritance sustained by a Trypanosoma brucei variant surface glycoprotein exclusion complex

Monoallelic expression of variant surface glycoprotein genes (VSGs) is essential for immune evasion by Trypanosoma brucei. Here, Faria et al. show that the VEX protein complex controls VSG allelic exclusion, and that CAF‐1 sustains inheritance of the VEX‐complex in association with the active VSG.

書目詳細資料

Principais autores:	Joana Faria, Lucy Glover, Sebastian Hutchinson, Cordula Boehm, Mark C. Field, David Horn
格式:	Artigo
語言:	Inglês
出版:	Nature Portfolio 2019-07-01
叢編:	Nature Communications
在線閱讀:	https://doi.org/10.1038/s41467-019-10823-8
標簽:	添加標簽 沒有標簽, 成為第一個標記此記錄!