A pivot-tether model for nucleosome recognition by the chromosomal passenger complex

Abstract Spatial restriction of Aurora B to T3-phosphorylated histone H3 (H3pT3) nucleosomes adjacent to centromeres during prometaphase and metaphase enables it to phosphorylate proteins necessary for spindle assembly checkpoint signalling and biorientation of chromosomes on the mitotic spindle. Au...

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主要な著者:	Reinis R Ruza, Chyi Wei Chung, Danny B H Gold, Michela Serena, Emile Roberts, Ulrike Gruneberg, Francis A Barr
フォーマット:	Artigo
言語:	Inglês
出版事項:	Springer Nature 2025-07-01
シリーズ:	EMBO Reports
主題:	Mitosis Spindle Assembly Checkpoint Centromeres Aurora Kinase B Nucleosomes
オンライン･アクセス:	https://doi.org/10.1038/s44319-025-00523-4
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