Highly potent C-type nanoantibodies neutralize Nipah and Hendra viruses by cavity filling on fusion glycoprotein

Abstract Nipah (NiV) and Hendra (HeV) viruses pose a serious threat, causing global outbreaks with high fatality rates. The fusion (F) glycoprotein, located on the viral surface, presents a conserved and promising neutralizing target. Here, we identify two C-type nanoantibodies (C-Nabs), 1A1-3-22 an...

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Detalhes bibliográficos

Principais autores:	Shengdong Wang, Guibo Rao, Xinghai Zhang, Yanfeng Yao, Li Chen, Shaohong Chen, Haiwei Zhang, Hang Liu, Miaoyu Chen, Wujian Li, Sheng Cao, Sandra Chiu, Rui Gong
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2026-05-01
coleção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-026-73406-4
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