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Treatment of Painful Palmoplantar Keratoderma Related to Pachyonychia Congenita Using EGFR Inhibitors

Pachyonychia congenita (PC) is a genodermatosis associated with severe painful palmoplantar keratoderma (PPK) and thickened dystrophic nails caused by autosomal dominant-negative mutations in five genes encoding keratins 6A-B-C, 16, and 17. The mechanical, surgical, or medical options for painful PC...

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Principais autores: Céline Greco, Anne-Charlotte Ponsen, Stéphanie Leclerc-Mercier, Joël Schlatter, Salvatore Cisternino, Claude Boucheix, Christine Bodemer
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-04-01
Serier:Biomedicines
Fag:
pachyonychia congenita
palmoplantar keratoderma
pain
EGFR
tyrosine kinase inhibitors
Online adgang:https://www.mdpi.com/2227-9059/10/4/841
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