⁶⁸Ga-Labeled [Thz¹⁴]Bombesin(7–14) Analogs: Promising GRPR-Targeting Agonist PET Tracers with Low Pancreas Uptake

With overexpression in various cancers, the gastrin-releasing peptide receptor (GRPR) is a promising target for cancer imaging and therapy. However, the high pancreas uptake of reported GRPR-targeting radioligands limits their clinical application. Our goal was to develop ⁶⁸Ga-labeled ago...

Fuld beskrivelse

Bibliografiske detaljer

Principais autores:	Lei Wang, Ivica Jerolim Bratanovic, Zhengxing Zhang, Hsiou-Ting Kuo, Helen Merkens, Jutta Zeisler, Chengcheng Zhang, Ruiyan Tan, François Bénard, Kuo-Shyan Lin
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2023-02-01
Serier:	Molecules
Fag:	gastrin-releasing peptide receptor agonist positron emission tomography Gallium-68 pancreas uptake
Online adgang:	https://www.mdpi.com/1420-3049/28/4/1977
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