Clinical Features and PTCH1 Expression in Gorlin–Goltz Syndrome: A Case Report

<b>Background and Clinical Significance:</b> Basal cell nevoid carcinoma syndrome, or Gorlin–Goltz Syndrome (GGS), is a genetic disease caused by germline mutations in genes involved in the Sonic HedgeHog (SHH) signaling pathway, mainly in the PTCH1 gene. PTCH1 is a receptor for SHH, and the activat...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Gabriela González-López, Samuel Mendoza-Álvarez, Claudia Patricia Mejia-Velazquez, Carla Monserrat Ramírez-Martínez, Alejandro Alonso-Moctezuma, Luis Fernando Jacinto-Alemán
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2025-03-01
Serija:	Reports
Teme:	Gorlin–Goltz syndrome odontogenic keratocysts PTCH1 RT-PCR basal cell carcinoma
Online dostop:	https://www.mdpi.com/2571-841X/8/1/34
Oznake:	Označite Brez oznak, prvi označite!