Assay for galactose-deficient IgA1 enables mechanistic studies with primary cells from IgA nephropathy patients

Aims: IgA nephropathy, the most common primary glomerulonephritis worldwide, is characterized by glomerular deposition of galactose-deficient IgA1 and elevated serum levels of this IgA1 glycoform. Current ELISA methods lack sensitivity to assess galactose deficiency using small amounts of IgA1, whic...

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Bibliografski detalji

Glavni autori:	Colin Reily, Dana V Rizk, Bruce A Julian, Jan Novak
Format:	Artigo
Jezik:	Inglês
Izdano:	Taylor & Francis Group 2018-08-01
Serija:	BioTechniques
Teme:	autoimmunity chemiluminescence colorimetric assay ELISA galactose-deficient IgA1 glycosylation
Online pristup:	https://www.future-science.com/doi/10.2144/btn-2018-0042
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