Integrative immunogenomic profiling identifies CALU as a brown adipocyte–linked modulator of progression and treatment response in pancreatic cancer

Abstract Obgective Pancreatic Ductal Adenocarcinoma (PDAC) remains a lethal malignancy with limited therapeutic options. This study aimed to identify brown adipocyte-related genes (BARGs) influencing PDAC prognosis and explore their roles in the tumor microenvironment (TME) and immunotherapy respons...

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Detalhes bibliográficos

Principais autores:	Fang Wu, Xufan Cai, Zhenyuan Qian, Guangyuan Song, Xiao Zhang, Tao Ding, Weilang Xu, WeiLin Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Springer 2026-01-01
Colecção:	Discover Oncology
Assuntos:	Pancreatic ductal adenocarcinoma (PDAC) CALU Tumor microenvironment Immunotherapy Prognosis
Acesso em linha:	https://doi.org/10.1007/s12672-025-04309-x
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