Critical cysteines in the functional interaction of adenylyl cyclase isoform 6 with Gαs

Abstract Activation of adenylyl cyclases (ACs) by G‐protein Gαs catalyzes the production of cyclic adenosine monophosphate (cAMP), a key second messenger that regulates diverse physiological responses. There are 10 AC isoforms present in humans, with AC5 and AC6 proposed to play vital roles in cardi...

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Principais autores:	Anjali Y. Bhagirath, Vikram Bhatia, Manoj Reddy Medapati, Nisha Singh, Martha Hinton, Prashen Chelikani, Shyamala Dakshinamurti
Format:	Artigo
Jezik:	Inglês
Izdano:	Wiley 2022-03-01
Serija:	FASEB BioAdvances
Teme:	adenylyl cyclase cyclic AMP cysteine G proteins mutational analysis
Online dostop:	https://doi.org/10.1096/fba.2021-00073
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