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Versatility of Liposomes for Antisense Oligonucleotide Delivery: A Special Focus on Various Therapeutic Areas

Nucleic acid therapeutics, specifically antisense oligonucleotides (ASOs), can effectively modulate gene expression and protein function, leading to long-lasting curative effects. The hydrophilic nature and large size of oligonucleotides present translational challenges, which have led to the explor...

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Principais autores: Raghav Gupta, Sagar Salave, Dhwani Rana, Bharathi Karunakaran, Arun Butreddy, Derajram Benival, Nagavendra Kommineni
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-05-01
Serier:Pharmaceutics
Fag:
antisense oligonucleotide
liposomes
delivery system
cationic lipids
ASO generations
Online adgang:https://www.mdpi.com/1999-4923/15/5/1435
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