Consecutive intrabronchial administration of Wharton’s jelly-derived mesenchymal stromal cells in ECMO-supported pediatric patients with end-stage interstitial lung disease: a safety and feasibility study (CIBA method)

Abstract Background Patients ineligible for lung transplant with end-stage Interstitial Lung Disease (ILD) on Extra-Corporeal Membrane Oxygenation (ECMO) face an appalling prognosis with limited therapeutic options. Due to the beneficial effect of Mesenchymal Stromal Cells (MSC) on inflammatory, imm...

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Автори:	Nerea Dominguez-Pinilla, Luis Ignacio González-Granado, Aitor Gonzaga, María López Diaz, Cecilia Castellano Yáñez, Clara Aymerich, Xabier Freire, Olga Ordoñez, Álvaro Gimeno Diaz de Atauri, María Salomé Albi Rodríguez, Elisa Martínez López, Rodrigo Iñiguez, Olga Serrano Garrote, Almudena Castro Frontiñán, Etelvina Andreu, Ana María Gutierrez-Vilchez, Marga Anton-Bonete, Gema Martinez-Navarrete, Nerea Castillo-Flores, Cristina Prat-Vidal, Margarita Blanco, Rocío Morante Valverde, Eduardo Fernandez, Sergi Querol, Luis Manuel Hernández-Blasco, Sylvia Belda-Hofheinz, Bernat Soria
Формат:	Artigo
Мова:	Inglês
Опубліковано:	BMC 2025-04-01
Серія:	Stem Cell Research & Therapy
Предмети:	Cell therapy Extracorporeal membrane oxygenation (ECMO) Mesenchymal stromal cells (MSC) Bronchoscopy Interstitial lung disease Bronchus associated lymphoid tissue (BALT)
Онлайн доступ:	https://doi.org/10.1186/s13287-025-04289-3
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