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Tsg101 UEV Interaction with Nedd4 HECT Relieves E3 Ligase Auto-Inhibition, Promoting HIV-1 Assembly and CA-SP1 Maturation Cleavage

Tsg101, a component of the endosomal sorting complex required for transport (ESCRT), is responsible for recognition of events requiring the machinery, as signaled by cargo tagging with ubiquitin (Ub), and for recruitment of downstream acting subunits to the site. Although much is known about the lat...

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Gardado en:
Principais autores: Susan M. Watanabe, David A. Nyenhuis, Mahfuz Khan, Lorna S. Ehrlich, Irene Ischenko, Michael D. Powell, Nico Tjandra, Carol A. Carter
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2024-10-01
Series:Viruses
Assuntos:
ESCRT
HIV-1
Nedd4
Tsg101
UEV domain
ubiquitin
Acceso en liña:https://www.mdpi.com/1999-4915/16/10/1566
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