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A syngeneic spontaneous zebrafish model of tp53-deficient, EGFRvIII, and PI3KCAH1047R-driven glioblastoma reveals inhibitory roles for inflammation during tumor initiation and relapse in vivo

High-throughput vertebrate animal model systems for the study of patient-specific biology and new therapeutic approaches for aggressive brain tumors are currently lacking, and new approaches are urgently needed. Therefore, to build a patient-relevant in vivo model of human glioblastoma, we expressed...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Alex Weiss, Cassandra D'Amata, Bret J Pearson, Madeline N Hayes
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications Ltd 2024-07-01
Cyfres:eLife
Pynciau:
Mynediad Ar-lein:https://elifesciences.org/articles/93077
Tagiau: Ychwanegu Tag
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