Systemic infection by Candida albicans requires FASN-α subunit induced cell wall remodeling to perturb immune response.

Invasive fungal infections are a leading cause of mortality and morbidity in patients with severely impaired host defenses, while treatment options remain limited. Fatty acid synthase (FASN), the key enzyme regulating de novo biosynthesis of fatty acids, is crucial for the lethal infection of fungi;...

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Váldodahkkit:	Yajing Zhao, Zhishan Zhou, Guiyue Cai, Dandan Zhang, Xiaoting Yu, Dongmei Li, Shuixiu Li, Zhanpeng Zhang, Dongli Zhang, Jiyao Luo, Yunfeng Hu, Aili Gao, Hong Zhang
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Public Library of Science (PLoS) 2025-03-01
Ráidu:	PLoS Pathogens
Liŋkkat:	https://doi.org/10.1371/journal.ppat.1012865
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