Synthesis and Evaluation of (1,4-Disubstituted)-1,2,3-triazoles as Estrogen Receptor Beta Agonists

Estrogen receptors (ER) are nuclear hormone receptors which are responsible for sex hormone signaling in women. A series of (1,4-disubstituted)-1,2,3-triazoles <b>5</b>–<b>21</b> were prepared by reaction of azidophenols with terminal alkynes under Fokin reaction conditions. The products were purifi...

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Principais autores:	Edward A. Wetzel, Grace C. Corriero, Sandra Brown-Ford, Daniel S. Sem, William A. Donaldson
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2022-08-01
Series:	Scientia Pharmaceutica
Assuntos:	estrogen receptor ligand alkyne–azide cycloaddition molecular docking
Acceso en liña:	https://www.mdpi.com/2218-0532/90/3/46
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