Intronic tRNAs of mitochondrial origin regulate constitutive and alternative splicing

Abstract Background The presence of nuclear mitochondrial DNA (numtDNA) has been reported within several nuclear genomes. Next to mitochondrial protein-coding genes, numtDNA sequences also encode for mitochondrial tRNA genes. However, the biological roles of numtDNA remain elusive. Results Employing...

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Detalles Bibliográficos

Principais autores:	Simon M. Hoser, Anne Hoffmann, Andreas Meindl, Maximilian Gamper, Jörg Fallmann, Stephan H. Bernhart, Lisa Müller, Melanie Ploner, Matthias Misslinger, Leopold Kremser, Herbert Lindner, Stephan Geley, Heiner Schaal, Peter F. Stadler, Alexander Huettenhofer
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2020-12-01
Series:	Genome Biology
Assuntos:	nimtRNA tRNA-lookalikes Intronic splicing enhancer (ISE) Splicing regulatory element numtDNA tRNA
Acceso en liña:	https://doi.org/10.1186/s13059-020-02199-6
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