Phase‐Separation of YAP Mediates AJUBA Super Enhancer Activation to Promote Aberrant Mitosis in Breast Cancer

Abstract Aberrant mitosis is a hallmark of cancer, which drives chromosomal instability, gene dysregulation, tumor heterogeneity, immune evasion, and therapy resistance. In this study, it is observed that dysregulation of YAP signaling can cause supernumerary centrosome clustering, thereby triggerin...

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Bibliografski detalji

Glavni autori:	Rui Zhang, Qingwen Huang, Zhuo Chen, Weijian Meng, Hongliang Dong, Zhihong Qi, Liang Liu, Jie Shen, Daxing Xie
Format:	Artigo
Jezik:	Inglês
Izdano:	Wiley 2026-02-01
Serija:	Advanced Science
Teme:	aberrant mitosis AJUBA breast cancer super enhancers YAP
Online pristup:	https://doi.org/10.1002/advs.202409341
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