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Iron Dysregulation in Alzheimer’s Disease: LA-ICP-MS Bioimaging of the Distribution of Iron and Ferroportin in the CA1 Region of the Human Hippocampus

Alzheimer’s disease (AD) is a prevalent neurodegenerative disorder characterized by cognitive decline and neuropathological hallmarks, including β-amyloid (Aβ) plaques, Tau tangles, synaptic dysfunction and neurodegeneration. Emerging evidence suggests that abnormal iron (Fe) metabolism plays a role...

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Principais autores: Susana Junceda, María Cruz-Alonso, Beatriz Fernandez, Rosario Pereiro, Eva Martínez-Pinilla, Ana Navarro
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-03-01
Serier:Biomolecules
Fag:
Alzheimer’s disease
iron transport proteins
ferroportin
iron homeostasis
β-amyloid
Tau
Online adgang:https://www.mdpi.com/2218-273X/14/3/295
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