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Formulation and In Vitro Evaluation of Mucoadhesive Sustained Release Gels of Phytoestrogen Diarylheptanoids from <i>Curcuma comosa</i> for Vaginal Delivery

Diarylheptanoids (DAs) characterized by a 1,7-diphenylheptane structural skeleton are considered a novel class of phytoestrogens. The DAs available in <i>Curcuma comosa</i> Roxb. (<i>C. comosa</i>) extract demonstrated significant estrogenic activities both in vitro and in vivo. This study aimed to...

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Hlavní autoři: Ekapol Limpongsa, Peera Tabboon, Sarunya Tuntiyasawasdikul, Bungorn Sripanidkulchai, Thaned Pongjanyakul, Napaphak Jaipakdee
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2023-01-01
Edice:Pharmaceutics
Témata:
<i>Curcuma comosa</i>
phytoestrogens
mucoadhesive gels
polyacrylic acid
vaginal gels
zero-order release
On-line přístup:https://www.mdpi.com/1999-4923/15/1/264
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