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RhoC regulates radioresistance via crosstalk of ROCK2 with the DNA repair machinery in cervical cancer

Abstract Background Radioresistance remains a challenge to the successful treatment of various tumors. Intrinsic factors like alterations in signaling pathways regulate response to radiation. RhoC, which has been shown to modulate several tumor phenotypes has been investigated in this report for its...

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Detalhes bibliográficos
Principais autores: Annapurna Pranatharthi, Pavana Thomas, Avinash H. Udayashankar, Chandra Bhavani, Srinag Bangalore Suresh, Sudhir Krishna, Jayashree Thatte, Nirmala Srikantia, Cecil R. Ross, Sweta Srivastava
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-09-01
Colecção:Journal of Experimental & Clinical Cancer Research
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Acesso em linha:http://link.springer.com/article/10.1186/s13046-019-1385-7
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