Epstein-Barr virus BNRF1 destabilizes SMC5/6 cohesin complexes to evade its restriction of replication compartments

Summary: Epstein-Barr virus (EBV) persistently infects people worldwide. Delivery of ∼170-kb EBV genomes to nuclei and use of nuclear membrane-less replication compartments (RCs) for their lytic cycle amplification necessitate evasion of intrinsic antiviral responses. Proteomics analysis indicates t...

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Detalhes bibliográficos

Principais autores:	Stephanie Pei Tung Yiu, Rui Guo, Cassie Zerbe, Michael P. Weekes, Benjamin E. Gewurz
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2022-03-01
coleção:	Cell Reports
Assuntos:	structural maintenance of chromosomes herpesvirus tegument lytic reactivation R-loop viral replication compartment
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211124722001358
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